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Chemical structure-based small molecule targeting Apex software is designed to answer a simple question: *Is my molecule in my sample?* By comparing spectral features predicted from molecular structure with experimental MS and MS/MS data, Apex can quickly analyze entire datasets to determine which of a set of structures is present in the sample. Application areas include metabolite ID, combinatorial library deconvolution, confirmation of synthesis, target compound analysis, competitive drug binding assays, or any other structure confirmation application
Vendor formats Agilent Technologies - Ion Trap, LC/MSD, ChemStation, Mass Hunter AB Sciex - Analyst, Analyst-QS, Data Explorer Bruker Daltronics - Compass, XMASS Jeol - Mass Center (TOF), QMS1000 NHMFL/Florida State University - MIDAS Shimadzu Biotech - LCMS-IT-TOF Thermo Scientific - Xcalibur Waters - MassLynx	Features Raw data import from most vendor formats Structure import from MOL and SDF files Support for combined MS and MS/MS experiments Simultanious use of + / - polarities Full support for high resolution and mass accuracy measurements Support multiple adducts, neutral losses, oligomers, multiple charge states.
MS Plugin for Mestrelab's Mnova Suite In partnership with Mestrelab Research, Sierra has reached a frution with the release of the new Mnova MS plugin for Mestrelab's widely acclaimed Mnova software suite. More info

Polymerix The leading software for polymer molecular weight measurement by Mass Spectrometry The standard for characterizing homopolymer and copolymer molecular weight distribution, polydispersity and mixture deconvolution. Composition and deconvolution of homopolymers and copolymer mixtures including Mn, Mw, Mz, PD, DPn, DPw, DPz values		Vendor formats as above plus XML - mzXML, mzData ASCII - Peak m/z-intensity

	Composer World-class software for Petroleomics data analysis and visualization. What's in an oil drop? Explore by clicking on the picture More info.

DXMS Automated data reduction and analysis for Hydrogen-Deuterium Exchange Mass Spectromery. DXMS automates the tedious process of finding and determining peptide deuteration levels in complex LC/MS datasets. Developed for and licensed from the University of California at San Diego and used by leading researchers in protein structure, binding, and interaction, DXMS is the only commercially-available and supported product in this field. H/D exchange instrument soon available from Biomotif	Features Raw data import from vendor formats (above) Proteine sequence import from FASTA and Swiss-Prot files Peptide identification import from SEQUEST result files Ability to track an unlimited number of peptides across multiple pools and experiments Automated location and refinement of peptide elution profiles Automated determination of peptide isotopic envelopes and centeroids Support for on-exchange and off exchange with EX2 kinetics Batch mode processing of multiple timepoint experiments

Chemalys 2010-01-29