| DART (Direct Analys Reals Time) |
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Mass Spectrometry Analysis without sample preparation |
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New
DART-SVP
Fixed position
DART-SVP-ET
Adjustable angle |
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Application areas
- forensic science
- food analysis
- homeland security
- product control
- process controll
- medicinal chemistry
- sythetic chemistry
- polymers & packings
- parfumes & cosmetics
- odur investigations
- oil (food and mineral)
- grease & creams
- try it at LSM lab
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Principle
These reactions in gas phase will simplify the MS-spectra giving nearly only the M+ or MH+ ions |
Features
- The simplest sampling procedure. There are a variety of sample holders to automatically move or hold the sample in front of the gas stream and acquire spectra
- No sample preparation is necessary. Solids, liquids and vapours can be analysed as seen
- No reagents or solvents are required. The only variable is the temperature of the gas stream. Once the correct temperature is achieved, spectra are produced instantaneously.
- Because there are no reagents, there are no background ions so everything detected originates in the sample
- DART can be fitted to most mass spectrometers with an ESI or APCI source including Thermo-Finnigan, Agilent, Bruker, ABI and Waters
- SVP Controller handle gas, temperature etc. controlled by iPod
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| DART Bibliography (reference list utdated July 2010) |
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Dart was invented by Cody & Laramée in 2005
DART "Direct Analysis in Real Time" is an Ionization Technique for Mass Spectrometry.
This is a revolutionary new ionization technique for rapid non-contact analysis of samples without any sample preparation.
DART is operating at ambient pressure at the ground potential and gives, together with a high resolution (R=6000) Time Of Flight instrument an almost instant composition of the sample. |
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Read the article by clicking on the picture
Everything on the picture has been analyzed with DART
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DART Flexible Sampling Options
Unlike most ionisation techniques, DART requires no sample preparation and spectra are obtained from untreated samples. Tablets, TLC plates, packaging and foodstuffs are just a few examples we have analysed directly. To accomodate the many different sample shapes and states, Ionsense have developed a range of sample holders which are easily attached to the motorised rail to simplify and automate analysis. Some of the different sample holders currently available are shown below. |
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With adjustalbe angle |
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Thin Layer Chromatography (TLC) plate holder
- Spring loaded plate holder makes it easy to change plates
- Motorized rail moves TLC-plate across Dart ionization beam
- Suitable for borh preparative and anaytical TLC-plates
- Can be used to hold microscope slides etc.
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Liquid Analysis
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- Use a melting point tube
- Dip it into the liquid
- Optimum position
- Moved into the gas stream either manual or by the motorized rail
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- Spectra are produced instantaneosly
- Samples and reference samples can be run simultaniously for accurate mass measurement
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Multiple Liquid Sample Analysis
- Up to 12 samples in the holder
- Spacing of DIPit holder allows sampling from multi-well plates
- Mororized rail moves samples into gas stream on-by-one
- 12 samples < 1 min
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DIPit |
| For use with CTC autoinjector or multiple sample holder |
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Tablet analysis
- Holds multiple tablets large or small
- Motorised rail moves automatically to next tablet
- Thermal stability studies through variation of gas temperature
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Adjustable Tweezers
- Spring-loaded grip for irregularly-shaped objects
- Ideal for plant material
- Analysis of ready products like chips
- Simplifies forensic analysis of clothing and other material
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| Information on this page from IonSense, KR Analytical and Jeol USA |
| back |
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| Chemalys
2010-08-16 |
